Clinical Pharmacy Polycythemia Vera Polycythemia vera (PV) is a Philadelphia chromosome-negative (Ph-) myeloproliferative neoplasm (MPN) characterized by JAK-STAT pathway activation and trilineage myeloproliferation with a predominant increase in red blood cell mass.
Members only Clinical Pharmacy Featured Direct Oral Anticoagulant Transitions & Periprocedural Management
Health and Wellness Exercise Extends Life After Cancer Diagnosis New data published in NEJM last month showcases additional benefits of exercise not previously well described; extending survival in cancer patients.
Health and Wellness L-Theanine: An Effective Anxiolytic and Focus-enhancing Supplement? L-theanine is a naturally occurring amino acid that has been generating buzz for its proposed anxiolytic, focus-enhancing, and sleep-improving effects!
Science Receptor Highlight Series: Nuclear Receptors 🧬 Unlike the transmembrane receptors, nuclear receptors are found inside the cell, either within the nucleus or in the cytoplasm. These receptors bind with, most commonly, lipid-soluble ligands like steroid hormones, thyroid hormones, or fat-soluble vitamins, among others.
Science Receptor Highlight Series: Ligand-gated Ion channels LGICs are fast-acting receptors that open or close in direct response to ligand binding, allowing ions to flow into or out of the cell rapidly
Clinical Pharmacy Penicillin Panic: Are You Really Allergic? Many penicillin allergy labels are inaccurate, creating barriers to care. Learn how tools like PEN-FAST help de-label and improve treatment.
Health and Wellness Childhood Trauma - The ACE Study These findings are truly staggering, and I hope it's evident how impactful these childhood traumas can be for an individual. Though the ACE study has confounders and limitations, it provides a crucial foundation for ongoing conversation and future research.
Science Real-World Evidence in the Drug Approval Process This article explores the growing role of RWE in drug approvals, its benefits, challenges, and future implications for the pharmaceutical industry.
Science Beyond Capacity: Intro to Cognitive Load Theory Imagine your brain as a bucket, constantly filling up with new information each day. What happens when you fill it up too much? The abundance of new information is either “spilled” out in overflow or “drained” into a separate storage for safe keeping and future retrieval. This is the focus
Science Mycorrhizal Fungi - Friends of the Ecosystem Have you ever tried to live with others? Does it make you mad when they leave dishes in the sink constantly or let laundry pile up? Well, I don't care, and neither do these fungi!
Science How Stereotypes Bias Memory Explore how stereotypes bias memory through source monitoring errors. This article examines impacts on gender, sexual orientation, race, and age while offering strategies to challenge implicit biases and reduce harmful effects.
Science Creatine Uncovered: A Scientific Review of Its Role in Fitness and Health This article examines creatine’s history, mechanism of action, clinical evidence, and areas of ongoing research.
Health and Wellness Lion's Mane - Not Just an Animal Apparently Phylogenetically more closely related to humans than plants, mushrooms are incredibly diverse and have resurged in popularity in recent decades for their nutritional and supplemental benefits.
Science FDA Oncologic Drug Advisory Committee: October 5th, 2023 Learn about FDA's Oncologic Drug Advisory Committee (ODAC), its role in reviewing oncology drugs, and insights on the October 2023 sotorasib meeting.
Health and Wellness Wearable Wellness: How the Oura Ring May Enhance Patient Care in Pharmacy Practice By focusing on sleep, health metrics, and activity, the Oura Ring may provide a holistic approach to health tracking.
Science How the Polio Vaccine Paralyzed Hundreds of Children, Eroding Public Trust in Government Health Policy One of the greatest scientists in American history is Dr. Jonas Salk, known today for establishing the prestigious Salk Institute in San Diego, California, and for discovering the polio vaccine. Dr. Salk is one of the few scientists ever to be put on the cover of Time Magazine, along with
Health and Wellness The Nurture of Intelligence: Insights from the Terman Study Whatever your definition of success, it is clear that values, habits, and support systems play a crucial role in shaping one's ability to achieve it.
Science Receptor Highlight Series: G-protein Coupled Receptors G-protein coupled receptors have an extensive history in drug discovery. Join me in learning more about the individual subtypes and their functions!
Science FDA and CDER: New Drug Therapy Approvals 2023 Today we dive in the Center for Drug Evaluation and Research (CDER) New Drug Therapy Reports from 2023 and the future implications of these new approvals!
Science Cancer + Telomerase = Immortality? Unlike cultures taken from other patients, the "HeLa" cells continued to divide and replicate indefinitely, thus becoming the first "immortal" cell line.
Health and Wellness Hydration Supplements for Optimal Performance As we dive into the nuances of the use of hydration supplements for optimal performance, keep in mind that all patients require personalized attention and needs, as there is no one-size-fits all!
Health and Wellness Harnessing Neuroplasticity: The Super Power You Didn't Know You Had Use your brain’s superpower to your advantage. It can do some pretty miraculous things, and so can you.
Science Are Seed Oils Bad For You? Seed oils have a bad reputation in the media and are thought to lead to inflammation and chronic disease. What does the data say about this? Are seed oils the enemy?
Science Marijuana: Endocannabinoid System Explained The ECS and their endocannabinoids act to modulate the release of neurotransmitters, regulate pain perception, interplay within the immune system, aid in the balance of metabolism and energy balance, and have a function in maintaining neuronal health and promotion of new neurons.